Clinical microCT


Oliver Bock, Hendrikje Börst, Gisela Beller, Gabriele Armbrecht, Corina Degner, Peter Martus, Heinz-Jürgen Roth, Dieter Felsenberg
Impact of oral ibandronate 150 mg once monthly on bone structure and density in postmenopausal osteoporosis or osteopenia derived from in vivo μCT
Bone Volume 50, Issue 1, January 2012, Pages 317-324


Albrecht W. Popp, Markus Windolf, Christoph Senn, Andrea Tami, R. Geoff Richards, Stefano Brianza, Damiano Schiuma
Prediction of bone strength at the distal tibia by HR-pQCT and DXA
Bone Volume 50, Issue 1, January 2012, Pages 296-300


L. Slatkovska, S. Alibhai, J. Beyene, H. Hu, A. Demaras, A. M. Cheung
Effect of 12 Months of Whole-Body Vibration Therapy on Bone Density and Structure in Postmenopausal Women: A Randomized Trial
Annals of Internal Medicin, November 15, 2011 vol. 155 no. 10 668-679


S. Boutroy , N. Vilayphiou, J-P Roux, P. D. Delmas, H. Blain, R. D. Chapurlat, P. Chavassieux
Comparison of 2D and 3D bone microarchitecture evaluation at the femoral neck, among postmenopausal women with hip fracture or hip osteoarthritis
Bone Volume 49, Issue 5, November 2011, Pages 1055-1061


JB. Pialat, A.J. Burghardt, M. Sode , T.M. Link, S. Majumdar
Visual grading of motion induced image degradation in high resolution peripheral computed tomography: Impact of image quality on measures of bone density and micro-architecture
Bone Volume 50, Issue 1, January 2012, Pages 111-118


Y. Wang, S. K. Boyd,M. C Battié,Y. Yasui, T. Videman
Is greater lumbar vertebral BMD associated with more disk degeneration? A study using µCT and discography
Journal of Bone and Mineral Research Volume 26, Issue 11, pages 2785–2791, November 2011


A. C. Ng, S. Khosla, N. Charatcharoenwitthaya, S. K. Kumar, S. J. Achenbach, M.F. Holets, L. K. McCready, L. J. Melton III, R. A. Kyle, S. V. Rajkumar, M. T. Drake
Bone microstructural changes revealed by HRpQCT imaging and elevated DKK1 and MIP-1α levels in patients with monoclonal gammopathy of undetermined significance
Blood October 31, 2011

Gabriele Armbrecht et al.
Trabecular and cortical bone density and architecture in women after 60 days of bed rest using high-resolution pQCT: WISE 2005
JBMR, Volume 26, Issue 10, pages 2399–2410, October 2011


X Sherry Liu, Elizabeth Shane, Donald J McMahon, X Edward Guo
Individual trabecula segmentation (ITS)–based morphological analysis of microscale images of human tibial trabecular bone at limited spatial resolution
JBMR, Volume 26, Issue 9 (September 2011), p 2184-2193


Salman Kirmani, Elizabeth J Atkinson, L Joseph Melton, B Lawrence Riggs, Shreyasee Amin, Sundeep Khosla
Relationship of testosterone and osteocalcin levels during growth
JBMR, Volume 26, Issue 9 (September 2011), p 2212-2216


Marcella D Walker, X Sherry Liu, Emily Stein, Bin Zhou, Ervis Bezati, Donald J McMahon, Julia Udesky, George Liu, Elizabeth Shane, X Edward Guo, John P Bilezikian
Differences in bone microarchitecture between postmenopausal Chinese-American and white women
JBMR, Volume 26, Issue 7 (July 2011), p 1392-1398


Qingju Wang, Ali Ghasem-Zadeh, Xiao-Fang Wang, Sandra Iuliano-Burns, Ego Seeman
Trabecular bone of growth plate origin influences both trabecular and cortical morphology in adulthood
JBMR, Volume 26, Issue 7 (July 2011), p 1577-1583


Banu B. Kalpakcioglu, Klaus Engelke, Harry K. Genant
Advanced imaging assessment of bone fragility in glucocorticoid-induced osteoporosis 
Bone, Volume 48, Issue 6, 1 June 2011, Pages 1221-1231

Thomas L. Mueller, David Christen, Steve Sandercott, Steven K. Boyd, Bert van Rietbergen, Felix Eckstein, Eva-Maria Lochmüller, Ralph Müller, G. Harry van Lenthe
Computational finite element bone mechanics accurately predicts mechanical competence in the human radius of an elderly population 
Bone, Volume 48, Issue 6, 1 June 2011, Pages 1232-1238


Miki Sode, Andrew J. Burghardt, Jean-Baptiste Pialat, Thomas M. Link, Sharmila Majumdar
Quantitative characterization of subject motion in HR-pQCT images of the distal radius and tibia 
Bone, Volume 48, Issue 6, 1 June 2011, Pages 1291-1297


Pawel Szulc et al.
Cross-sectional analysis of the association between fragility fractures and bone microarchitecture in older men: The STRAMBO study
JBMR, Volume 26, Issue 6, pages 1358–1367, June 2011


Szulc P, Hawa G, Boutroy S, Vilayphiou N, Schoppet M, Chapurlat R, Hofbauer LC.
Cortical Bone Status Is Associated with Serum Osteoprotegerin Concentration in Men: The STRAMBO Study.
J Clin Endocrinol Metab. 2011 May 11


Bacchetta J, Boutroy S, Vilayphiou N, Ranchin B, Fouque-Aubert A, Basmaison O, Cochat P.
Bone assessment in children with chronic kidney disease: data from two new bone imaging techniques in a single-center pilot study.
Pediatr Nephrol. 2011 Apr;26(4):587-95


McKay H, Liu D, Egeli D, Boyd S, Burrows M.
Physical activity positively predicts bone architecture and bone strength in adolescent males and females.
Acta Paediatr. 2011 Jan;100(1):97-101.


Macdonald HM, Nishiyama KK, Hanley DA, Boyd SK.
Changes in trabecular and cortical bone microarchitecture at peripheral sites associated with 18 months of teriparatide therapy in postmenopausal women with osteoporosis.
Osteoporos Int. 2011 Jan;22(1):357-62..


Burrows M, Liu D, Perdios A, Moore S, Mulpuri K, McKay H.
Assessing bone microstructure at the distal radius in children and adolescents using HR-pQCT: a methodological pilot study.
J Clin Densitom. 2010 Oct-Dec;13(4):451-5.


Shkolnikov YP, Bowden A, MacDonald D, Kurtz SM.
Wear pattern observations from TDR retrievals using autoregistration of voxel data.
J Biomed Mater Res B Appl Biomater. 2010 Aug;94(2):312-7.


 Burrows M, Liu D, Moore S, McKay H.
Bone microstructure at the distal tibia provides a strength advantage to males in late puberty: an HR-pQCT study.
J Biomed Mater Res B Appl J Bone Miner Res. 2010 Jun;25(6):1423-32.


Burrows M, Liu D, McKay H
High-resolution peripheral QCT imaging of bone micro-structure in adolescents.
Osteoporos Int. 2010 Mar;21(3):515-20. Epub 2009 Mar 26.


Cohen A, Dempster DW, Müller R, Guo XE, Nickolas TL, Liu XS, Zhang XH, Wirth AJ, van Lenthe GH, Kohler T, McMahon DJ, Zhou H, Rubin MR, Bilezikian JP, Lappe JM, Recker RR, Shane E.
Assessment of trabecular and cortical architecture and mechanical competence of bone by high-resolution peripheral computed tomography: comparison with transiliac bone biopsy.
Osteoporos Int. 2010 Feb;21(2):263-73. Epub 2009 May 20.


Stinus Hansen, Jens-Erik Beck Jensen, Lars Rasmussen, Ellen M. Hauge, and Kim Brixen
Effects on Bone Geometry, Density and Microarchitecture in the Distal Radius but not Tibia in Women with Primary Hyperparathyroidism. A case-control study using HR-pQCT
J Bone Miner Res 2010; March 25


E. Seeman, P.D. Delmas, D.A. Hanley, D. Sellmeyer, A.M. Cheung, E. Shane, A. Kearns, T. Thomas, S.K. Boyd, S. Boutroy, C. Bogado, S. Majumdar1, M. Fan, C. Libanati, and J. Zanchetta
Microarchitectural Deterioration of Cortical and Trabecular Bone: Differing Effects of Denosumab and Alendronate
J Bone Miner Res 2010; March


Sornay-Rendu E, Cabrera-Bravo JL, Boutroy S, Munoz F, Delmas PD.
Severity of vertebral fractures is associated with alterations of cortical architecture in postmenopausal women.
J Bone Miner Res. 2009 Apr;24(4):737-43.


Andrew J. Burghardt, Galateia J. Kazakia, Sweta Ramachandran, Thomas M. Link, Sharmila Majumdar
Age and Gender Related Differences in the Geometric Properties and Biomechanical Significance of Intra-­cortical Porosity in the Distal Radius and Tibia
J Bone Miner Res 2009; November


Christian M. Stach, Michael Bäuerle, Matthias Englbrecht, Gerhard Kronke, Klaus Engelke, Bernhard Manger and Georg Schett
Periarticular bone structure in rheumatoid arthritis patients and healthy individuals assessed by high resolution computed tomography
Arthritis & Rheumatism 2009


Ahi S. Issever, Thomas M. Link, Marie Kentenich, Patrik Rogalla, Karsten Schwieger, Markus B. Huber, Andrew J. Burghardt, Sharmila Majumdar, and Gerd Diederichs
Trabecular Bone Structure Analysis in the Osteoporotic Spine Using a Clinical In Vivo Setup for 64-Slice MDCT Imaging: Comparison to µCT Imaging and µFE Modeling
J Bone Miner Res 2009;24:1628-1637


Kyle K Nishiyama, Heather M Macdonald, Helen R Buie, David A Hanley, Steven K Boyd
Postmenopausal women with osteopenia have higher cortical porosity and thinner cortices at the distal radius and tibia than women with normal aBMD: an in vivo HRpQCT study
J Bone Miner Res (2009)


A. J. Burghardt, G. J. Kazakia, T. M. Link, S. Majumdar
Automated simulation of areal bone mineral density assessment in the distal radius from high-resolution peripheral quantitative computed tomography
J Osteoporos Int (2009) 20:2017–2024


Andreas Krebs, Christian Graeff, Isolde Frieling, Bodo Kurz, Wolfram Timm, Klaus Engelke, Claus-C. Glüer
High resolution computed tomography of the vertebrae yields accurate information on trabecular distances if processed by 3D fuzzy segmentation approaches
Bone 44 (2009) 145–152


Laurence Vico, Mohamed Zouch, Adel Amirouche, Delphine Frère, Norbert Laroche, Bruno Koller, Andres Laib, Thierry Thomas and Christian Alexandre
High-Resolution pQCT Analysis at the Distal Radius and Tibia, Discriminates Patients with Recent Wrist and Femoral Neck Fractures
J Bone Miner Res 2008;23:1741-1750


Joshua A. MacNeil, Steven K. Boyd
Bone strength at the distal radius can be estimated from high-resolution peripheral quantitative computed tomography and the finite element method
Bone 42 (2008) 1203-1213


Miki Sode, Andrew J. Burghardt, Robert A. Nissenson, Sharmila Majumdar
Resolution Dependence of the Non-metric Trabecular Structure Indices
Bone 42 (2008)728-736


E. Verhulp, B. Van Rietbergen, R. Huiskes
Load distribution in the healthy and osteoporotic human proximal femur during a fall to the side
Bone 42 (2008)30-35


Peter C. Strohm, David Kubosch, Thorsten A. Bley, Christoph M. Sprecher, Norbert P. Südkamp, Stefan Milz
Detection of Bone Graft Failure in Lumbar Spondylodesis: Spatial Resolution with High-Resolution Peripheral Quantitative CT
AJR:190, May 2008


Stephanie Boutroy, Bert Van Rietbergen, Elisabeth Sornay-Rendu, Francoise Munoz, Mary L Bouxsein, and Pierre D Delmas
Finite Element Analysis Based on In Vivo HR-pQCT Images of the Distal Radius Is Associated With Wrist Fractures in Postmenopausal Women
J Bone Miner Res 2008;23:392-399


Gabriella Milos, Anja Spindler, Peter Rüegsegger, Gregor Hasler, Ulrich Schnyder, Andres Laib, Luigi M. Gallo, Daniel Uebelhart, Hansjorg Hauselmann
Does weight gain induce cortical and trabecular bone regain in anorexia nervosa? A two-year prospective study
Bone 41 (2007)869-874


L Joseph Melton, B Lawrence Riggs, Tony M Keaveny, Sara J Achenbach, Paul F Hoffmann, Jon J Camp, Peggy A Rouleau, Mary L Bouxsein, Shreyasee Amin, Elizabeth J Atkinson, Richard A Robb, and Sundeep Khosla
Structural Determinants of Vertebral Fracture Risk
J Bone Miner Res 2007; Vol 22: 1885-1892


Kevin A. Davis, Andrew J. Burghardt, Thomas M. Link, Sharmila Majumdar
The Effects of Geometric and Threshold Definitions on Cortical Bone Metrics Assessed by In Vivo High-Resolution Peripheral Quantitative Computed Tomography
Calcif Tissue Int 2007


Stephanie Boutroy, Mary L Bouxsein, Francoise Munoz, and Pierre D Delmas
In Vivo Assessment of Trabecular Bone Microarchitecture by High-Resolution Peripheral Quantitative Computed Tomography
J of Clinical Endocrinology & Metabolism (2005)

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