Preclinical microCT



R. Prisby, A. Guignandon, A. Vanden-Bossche, F. Mac-Way, M-T Linossier, M. Thomas, N. Laroche, L. Malaval, M. Langer, ZA Peter, F. Peyrin, L. Vico, M-H Lafage-Prous
Intermittent PTH(1–84) is osteoanabolic but not osteoangiogenic and relocates bone marrow blood vessels closer to bone-forming sites
Journal of Bone and Mineral Research Volume 26, Issue 11, pages 2583–2596, November 2011


S. M Woo, J. Rosser, V. Dusevich, I. Kalajzic, L. F Bonewald
Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivo
Journal of Bone and Mineral Research Volume 26, Issue 11, pages 2634–2646, November 2011


V. Habauzit, S. M. Sacco, A. Gil-Izquierdo,  A. Trzeciakiewicz, C. Morand, D. Barron, S. Pinaud, E. Offord, M-N Horcajada
Differential effects of two citrus flavanones on bone quality in senescent male rats in relation to their bioavailability and metabolism
Bone Volume 49, Issue 5, November 2011, Pages 1108-1116


D.M. Smith, G.M. Cooper, A.M.  Afifi, M.P.  Mooney, J. Cray, P.J.  Rubin, K.G. Marra, J.E. Losee
Regenerative Surgery in Cranioplasty Revisited: The Role of Adipose-Derived Stem Cells and BMP-2
Plastic & Reconstructive Surgery, November 2011 - Volume 128 - Issue 5 - p 1053–1060


Louis Boell, Diethard Tautz
Micro-evolutionary divergence patterns of mandible shapes in wild house mouse (Mus musculus) populations
BMC Evolutionary Biology 2011, 11:306


J F Hainfeld, M J O’Connor, F A Dilmanian, D N Slatkin, D J Adams and H M Smilowitz
Micro-CT enables microlocalisation and quantification of Her2-targeted gold nanoparticles within tumour regions
British Journal of Radiology (2011) 84, 526-533


Graeme M. Campbell, Michael S. Ominsky and Steven K. Boyd
Bone quality is partially recovered after the discontinuation of RANKL administration in rats by increased bone mass on existing trabeculae: an in vivo micro-CT study
Osteoporosis International Volume 22, Number 3, 931-942


Jason R. Maher, Andrew J. Berger, Masahiko Takahata and Hani A. Awad
Raman spectroscopy detects deterioration in biomechanical properties of bone in a glucocorticoid-treated mouse model of rheumatoid arthritis
J. Biomed. Opt. 16, 087012 (Aug 16, 2011)


Isabelle Gennero et al
Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass
Bone, Volume 49, Issue 3, September 2011, Pages 395-403


Basem M Abdallah, Nicholas Ditzel, Amer Mahmood, Adiba Isa, Gunnhildur A Traustadottir, Arndt F Schilling, María-José Ruiz-Hidalgo, Jorge Laborda, Michael Amling, Moustapha Kassem
DLK1 is a novel regulator of bone mass that mediates estrogen deficiency–induced bone loss in mice
JBMR, Volume 26, Issue 7 (July 2011), p 1457-1471


Erik R Sampson et al
The orally bioavailable met inhibitor PF-2341066 inhibits osteosarcoma growth and osteolysis/matrix production in a xenograft model
JBMR, Volume 26, Issue 6, pages 1283–1294, June 2011


Songlin Peng et al.
Osteoprotegerin deficiency attenuates strontium-mediated inhibition of osteoclastogenesis and bone resorption
JBMR, Volume 26, Issue 6, pages 1272–1282, June 2011


Graeme M. Campbell, R. Bernhardt, D. Scharnweber, Steven K. Boyd
The bone architecture is enhanced with combined PTH and alendronate treatment compared to monotherapy while maintaining the state of surface mineralization in the OVX rat 
Bone, Volume 49, Issue 2, August 2011, Pages 225-232



Yi-Xin He, Ge Zhang, Xiao-Hua Pan, Zhong Liu, Li-zhen Zheng, Chun-Wai Chan, Kwong-Man Lee, Yong-Ping Cao, Gang Li, Lei Wei, Leung-Kim Hung, Kwok-Sui Leung, Ling Qin
Impaired bone healing pattern in mice with ovariectomy-induced osteoporosis: A drill-hole defect model 
Bone, Volume 48, Issue 6, 1 June 2011, Pages 1388-1400



Brouwers JE, van Rietbergen B, Ito K, Huiskes R.
Effects of vibration treatment on tibial bone of ovariectomized rats analyzed by in vivo micro-CT
J Orthop Res. 2010 Jan;28(1):62-9


Andreas Bauer, Eelco Verhulp, Stan Schoofs

Measuring Local Strains in Sandstones under Stress with Micro-computed Tomography
Advances in X-ray Tomography for Geomaterials (book, 2010)


J.S. Alwood, K. Yumoto, R. Mojarrab, C.L. Limoli, E.A.C. Almeida, N.D. Searby, R.K. Globus
Heavy ion irradiation and unloading effects on mouse lumbar vertebral microarchitecture, mechanical properties and tissue stresses
Bone 47 (2010) 248-255


Maya Fisher, Sharon Hyzy, Robert E. Guldberg, Zvi Schwartz, Barbara D. Boyan
Regeneration of bone marrow after tibial ablation in immunocompromised rats is age dependent
Bone 46 (2010) 396-401


Yves Pauchard, Corinne Mattmann, Andreas Kuhn, Jürg A. Gasser, Steven K. Boyd
European Society of Biomechanics S.M. Perren Award 2008: Using temporal trends of 3D bone micro-architecture to predict bone quality
Journal of Biomecanics 41 (2008) 2946-2953


X. Sherry Liu, Angela H. Huang, X. Henry Zhang, Paul Sajda, Baohua Ji, X. Edward Guo
Dynamic simulation of three dimensional architectural and mechanical alterations in human trabecular bone during menopause
Bone 43 (2008) 292-301


Helen R Buie, Christopher P Moore, and Steven K Boyd
Postpubertal Architectural Developmental Patterns Differ Between the L3 Vertebra and Proximal Tibia in Three Inbred Strains of Mice
J Bone Miner Res 2008; 23: 2048-2059


Uya Sabsovich, J. David Clark, Guochun Liao, Gary Peltz, Derek P. Lindsey, Christopher R. Jacobs, Wei Yao, Tian-Zhi Guo, Wade S. Kingery
Bone microstructure and its associated genetic variability in 12 inbred mouse strains: µCT study and in silico genome scan
Bone 42 (2008) 439-451


Eduardo K. Moioli, Paul A. Clark, D. Rick Sumner, Jeremy J. Mao
Autologous stem cell regeneration in craniosynostosis
Bone 42 (2008) 332 -340


Robert R Recker, Pierre D Delmas, Johan Halse, Ian R Reid, Steven Boonen, Pedro A Garcia-Hernandez, Jerzy Supronik, E Michael Lewiecki, Luis Ochoa, Paul Miller, Huilin Hu, Peter Mesenbrink, Fiorian Hartl, Juerg Gasser and Erik F. Eriksen
Effects of Intravenous Zoledronic Acid Once Yearly on Bone Remodeling and Bone Structure
J of Bone Miner Res 2008; 23: 6-16


Wei Yao, Zhiqiang Cheng, Kurt J. Koester, W. Ager, Mehdi Balooch, Aaron Pham, Salomon Chefo, Cheryl Busse, Robert 0. Ritchie, Nancy E. Lane
The degree of bone mineralization is maintained with single intravenous bisphosphonates in aged estrogen-deficient rats and is a strong predictor of bone strength
Bone 41 (2007)804-812


Brouwers, J.E.M, van Rietbergen, B., Huiskes, R.
In-vivo Micro-CT Radiation Does Not Affect Bone Structure in Rats.
52nd Annual Meeting of the Orthopaedic Research Society, 2006, Paper No. 1597


Jochen Zwerina, Kurt Redlich, Karin Polzer, Leo Joosten, Gerhard Kroenke, Joerg Distler, Andreas Hess, Noreen Pundt, Thomas Pap, Oskar Hoffmann, Juerg Gasser, Clemens Scheinecker, Josef S. Smolen, Wim van den Berg and Georg Schett
TNF-induced structural joint damage is mediated by IL-1
11742–11747; PNAS; July 10, 2007; vol. 104; no. 28


Klinck, R.J., Boyd, S.
The Effect of Radiation on Bone Architecture for in vivo Micro-computed Tomography.
52nd Annual Meeting of the Orthopaedic Research Society, 2006, Paper No. 1596


Xiaowei S Liu, Paul Sajda, Punam K Saha, Felix W Wehrli and X Edward Guo
Quantification of the Roles of Trabecular Microarchitecture and Trabecular Type in Determining the Elastic Modulus of Human Trabecular Bone
J Bone Miner Res, 21, 2006: 1608-1617


JA Gasser, P Ingold, K Grosios, A Laib, S Hämmerle, B Koller.
Non-invasive monitoring of changes in structural cancellous bone parameters with a novel prototype microCT.
J Bone Miner Metab, 23 (suppl), 2005:90-96.


David V., Laroche N, Boudignon B, Lafage-Proust M-H, Alexandre C., Rueegsegger P, Vico L.
Noninvasive In Vivo Monitoring of Bone Architecture Alterations in Hindlimb-Unloaded Female Rats Using Novel Three-Dimensional Microcomputed Tomography
J Bone Mineral Res 2003;18:1622-16

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